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The word is probably an aphetic form of either awer or arvaire. MED and OED suggest interpreting it as a figurative use of guerre ('conflict, trouble').
s.
estre en wer de
to be in a state of doubt, uncertainty, confusion about:
(
1280-1307; MS: s.xiv1
)
Des altercaciouns taunt dure fu l'endurer De pees ou de la gere le pople fu en wer
LANGTOFT thiol2 404.1979